FertilityTies posts tagged with chromosome

Pericentric inversion of chromosome 9

Tue, 05 Aug 2008 00:23:12 -0500

I have 3 normal healthy pregnancies which have been followed by 3 miscarriages (first trimester). I am now 4 weeks pregnant and found out today that I have a pericentric inversion of one chromosome 9. I did not feel reassured by my doctor. Also I had nausea throughout the first trimester in all 3 of my normal pregnancies. I had none, including no other pregnancy symptoms (besides a missed period) in the pregnancies that ended in miscarriage. I know it is not a guarentee of a healthy pregnancy but I am feeling nausea as well as other symptoms with this pregnancy. My doctor informed me that it is basically a waiting game and nothing can be done for now.

Is there any advice you can give me or lead me to?

Praying for the best

Chromosome 9,13,15

Sun, 20 Jul 2008 03:26:04 -0500

I have got my and my husband karyotype test.My husbands results are normal but my results indicates some minor abnormality(I have got these results on telephone if you desire i will use the exacts words as mentioned on report after i receive it) related to chromosome 9,13,15.

Can they be the cause of infertility if yes is their any solution.

Rupinderbal

miscarriages is from my chromosome 9 inversion?!?!

Mon, 14 Jul 2008 12:00:07 -0500

What do you know about chromosome 9 inversion?! And what can be done about it?! Is IVF the only way around it?!

Here's what has been going on w/me:Well my beta level was 15,876.8 hcg 7/9/08 & my ultrasound mesaured the baby @ 5w 6d... so my due date is now 3/5/09. Also I got some bad news from my RE on 7/9/08...he said that after testing & research...he's pretty sure the main cause of my recurrent miscarriages is from my chromosome 9 inversion (which is rare...& I knew about the inversion & @1 point we thought we might need IVF cuz of what a nurse had told us & then my RE had made us thought that it wasn't gonna require

IVF...even more rare is the fact both my husband & I have it...which us both having it...instead of only 1 of us having it is a good thing believe it or not!)& that since we both have it it's better than only 1 of us having it because their being more possibilities for the chromosomes to match up right...he told me the only reason my daughter was born(miracle!!)is because I just happened to drop an egg w/a set of chromosomes w/o the inversion..so it matched up....which is the only way she was able to surive cuz I needed to have 2 sets of chromosomes w/o inversion...& if I had dropped the chromosome 9 inversion it would have matched up wrong...& end in m/c. Well since my husband & I both have it the chances are better for it to match up(like a puzzle)...we either have to both give a set w/o inversion or both give a set w/inversion(if we did that though the child when it grew up would have infertility probs due to inversion), but if we both gave diff sets...1 w/o inversion & 1 w/inversion...it would mismatch...& I'll m/c again(or I think if it survived I might have a baby w/a lot of birth defects...according to 1 website...here's the link to the table that shows the type of defects:

:http://www.ijhg.com/viewimage.asp?img=IndianJHumGenet_2006_12_3_129_29856_4.jpg if it has that prob...it might have physical &/(or)mental probs,...but my RE had advised me that those type of probs depends on the serverity of the inversion & that are's weren't severe...but to me this inversion is rare...so since little is known...there are conflicting ideas...since there have been limted clinical studies).

The RE said that there's a test he could do @ 12weeks to find out if it's mismatched or not,...but by 12 weeks if the baby has that prob...I'll m/c b4 12weeks...& if I make it to 12weeks for testing...then I'm outta the clear & it doesn't have that problem. Also he suggested some meds to take,....but there was no guarantee it would work or help prevent m/c & have me carry full-term, but still I had to take time to take these meds into consideration b4 I ordered them & self-pay for it. Well today's 7/14/08 & I decided to order the meds...so tomorrow on 7/15/08 I have an appt w/my RE for prob another u/s(probably)& blood work(of course),& I'm gonna ask my RE how to take the meds when & how often. The new meds I was prescribed are: Lovenox 30MG (a blood thinner injection for my blood cloting problem..there's a side effect..of not being able to stop bleeding if I get injured though which really scares my husband & I!!!),Chorionic Gonado (HCG

multi-dose injection to help keep my HCG levels up...I assume??)...anywayz I'll have more info on 7/15/08 @ my appt.

All of this has been really hard on me...the 3 m/c's...the high risk pregnancy...the feeling of helplessness...cuz the RE can't do much for me till I get outta 1st trimester!!! It's so depressing to not know if ur baby will live or die...& the RE can't do anything about it really..since it's a chromosomal abnormalty...& I really wish there was more they could do for my baby & more research on it...& more info known!! Also I think even if I make it to 12weeks I still want the test...cuz I wanna know what I'm up against...where the baby has problems..or not we will love it uncondtionaly...I just want to be prepared if there's a problem...so I'm not suprised! Everyone pray for me!!!

Recurrent_MC_chick

Problems caused by having an extra X Chromosome

Fri, 04 Apr 2008 11:59:13 -0500

Drs., what effect will having an extra X chromosome have on my offsprings, or what problems etc. I havent been to a genetic counsellor yet but trying to research on this. By the way I am 35.

Saloj

Miscarriage Chromosome abnormality..will it happen again?

Tue, 29 Jan 2008 15:37:59 -0600

Dear Dr. Q,

My sister had a miscarriage at 12 weeks, and apparently it was due to an abnormality in Chromosome 22, what does that mean, and can she have in the future a normal pregnancy..a healthy boy or girl? Thank u! I hope there I can give her encouraging news...

Tania

Miscarige

Fri, 18 Jan 2008 17:17:44 -0600

Hello!

I have done 2 IVF with hatching I got pregnant, but at 6 weeks I had miscarige my HCG did not double. I did blood test, and even I took to fites to test and the test come back good. Could you please tell me what could be the reason for miscarige. Thank you in advance.

Basienka

Basienka