TTCing w/recurrent miscarriage due to chromosome 9 inversion & other probs!!
July 14, 2008
Well my beta level was 15,876.8 hcg 7/9/08 & my ultrasound mesaured the baby @ 5w 6d... so my due date is now 3/5/09. Also I got some bad news from my RE on 7/9/08...he said that after testing & research...he's pretty sure the main cause of my recurrent miscarriages is from my chromosome 9 inversion (which is rare...& I knew about the inversion & @1 point we thought we might need IVF cuz of what a nurse had told us & then my RE had made us thought that it wasn't gonna require
IVF...even more rare is the fact both my husband & I have it...which us both having it...instead of only 1 of us having it is a good thing believe it or not!)& that since we both have it it's better than only 1 of us having it because their being more possibilities for the chromosomes to match up right...he told me the only reason my daughter was born(miracle!!)is because I just happened to drop an egg w/a set of chromosomes w/o the inversion..so it matched up....which is the only way she was able to surive cuz I needed to have 2 sets of chromosomes w/o inversion...& if I had dropped the chromosome 9 inversion it would have matched up wrong...& end in m/c. Well since my husband & I both have it the chances are better for it to match up(like a puzzle)...we either have to both give a set w/o inversion or both give a set w/inversion(if we did that though the child when it grew up would have infertility probs due to inversion), but if we both gave diff sets...1 w/o inversion & 1 w/inversion...it would mismatch...& I'll m/c again(or I think if it survived I might have a baby w/a lot of birth defects...according to 1 website...here's the link to the table that shows the type of defects:
:http://www.ijhg.com/viewimage.asp?img=IndianJHumGenet_2006_12_3_129_29856_4.jpg if it has that prob...it might have physical &/(or)mental probs,...but my RE had advised me that those type of probs depends on the serverity of the inversion & that are's weren't severe...but to me this inversion is rare...so since little is known...there are conflicting ideas...since there have been limted clinical studies).
The RE said that there's a test he could do @ 12weeks to find out if it's mismatched or not,...but by 12 weeks if the baby has that prob...I'll m/c b4 12weeks...& if I make it to 12weeks for testing...then I'm outta the clear & it doesn't have that problem. Also he suggested some meds to take,....but there was no guarantee it would work or help prevent m/c & have me carry full-term, but still I had to take time to take these meds into consideration b4 I ordered them & self-pay for it. Well today's 7/14/08 & I decided to order the meds...so tomorrow on 7/15/08 I have an appt w/my RE for prob another u/s(probably)& blood work(of course),& I'm gonna ask my RE how to take the meds when & how often. The new meds I was prescribed are: Lovenox 30MG (a blood thinner injection for my blood cloting problem..there's a side effect..of not being able to stop bleeding if I get injured though which really scares my husband & I!!!),Chorionic Gonado (HCG
multi-dose injection to help keep my HCG levels up...I assume??)...anywayz I'll have more info on 7/15/08 @ my appt.
All of this has been really hard on me...the 3 m/c's...the high risk pregnancy...the feeling of helplessness...cuz the RE can't do much for me till I get outta 1st trimester!!! It's so depressing to not know if ur baby will live or die...& the RE can't do anything about it really..since it's a chromosomal abnormalty...& I really wish there was more they could do for my baby & more research on it...& more info known!! Also I think even if I make it to 12weeks I still want the test...cuz I wanna know what I'm up against...where the baby has problems..or not we will love it uncondtionaly...I just want to be prepared if there's a problem...so I'm not suprised! Everyone pray for me!!!
thank you so much for ur kind words, I'm praying that all goes well! I'm hoping @ my appt 2mmrow my u/s will show the baby has grown since last u/s & that my hcg will have risen & doubled again...so that will give me some comfort to know @ least that things are still progressing in my pregnancy...since 2 outta my 3 m/c's were "missed miscarriages"..where the dr didn't know it died till my u/s showed no heart beat & growth had stopped & hcg...had dropped! So I am extrmely neverous!!!
i to have to go on lovenox when i become pregnant. you should purchase a medical bracelet for everyone i s aware that you are on lovenox incase you are injured. there are drugs to reverse the lovenox. I had threee miscarriage to and i have mthfr and prothromobin factor II. that is why i am going on lovenox. my doctor just prescribe me clomid then on day 21 progesterone he is hoping it will fix my hormone problem
Oh so sorry for ur losses, it's nice to have someone else in my shoes..who's been through it also & I have total empthy for u! Iam on progestrone also...looks like weh ave a lot of medcial probs incommon.... I pray u get a BFP & that u also carry full-term! Thanks for the advice I will look into getting a medical bracelet..can I have 1 made up the same day I request it @ the pharmacy? Where should I purchase the mediacl bracelet any recommendations? Thank you for commenting!
hang in there hopeful...am praying everything works out just well for you, sometimes its just not a fair game, its one thing trying to get pregnant and when you do its another thing keeping it, just when u think things could not get any worse, i so appreciate stories like this because it makes you see how the tables can turn and how we must appreciate life and what it has to offer and we must be patient with the life itself. Hopeful you are in my prayers and thaughts i wish the lord would and hopeful he will bless you u lots of miracles. All the best my dear...and keep us posted. ((Hugs))
Thank you so much...ur kind words are very comforting...these losses have been hard on me & this pregnancy has really been hard on me...I'm having so many problems right now...& I'm pretty sure I'm starting to develop anmeia from this pregnancy..on top of other probs...I've started taking iron supplments along w/my prenantal, folic acid/B-12 & my other meds...etc. I've noticed when I take my iron in the beginnig of the day I feel ok till towards the end..but if I take it towards the end of the day...I feel light headed, tired, weak,...along w/some other symptoms...my dr...knows I just started taking iron...so if I still feel this way after taking iron...& it doesn't cure my symptoms...then they'll look into it. Anywayz pray for me everyone...cuz if iron pills don't work I'll need shots. Thanks 4 all the comments!
They detected a heart beat on u/s everyone! It was 115 bpm! And my due date changed again...to the 3/6/09 which would make me 6w 4d?! My RE said that I should keep the due date according to my LMP not the size though...cuz the baby could just be growing @ a slightly diff rate...right now & will even out soon..so I should stick w/dd 3/8/09...until I get futher along which would make me 6w 2d?! Not sure what my beta was though...cuz the lab results after 1:30pm...arn't avaliable till the following day...so if I can get back on 2mmrow I'll post it(cuz I'll be outta town for a few days). Keep praying for me...I'll post more l8r...& more info the RE told me 2...don't feel like writing it all right now...lol.
Ok I'm finally updating the rest of the info from 7/15/08....the beta HCG was 58,722 & the RE told me that since detected heart beat via u/s...that m/c satistics go down...& we found out if baby does have the chromosome prob...it has a chance for birth defects...what kind..he doesn't really know...I wish this chromosome 9 inversion wasn't so rare! Anywayz continue praying every body!



July 14, 2008