Hello Dr. Q
I am 27 years old and my husband and I have been TTC since 7 months. I was on BCP till Nov'07. I did not get periods for the month of Dec. I got periods starting Jan to March which were really irregular. I could not determine when was I ovulating. My Ob/Gyn referred me to an endocrinologist because i have hypothyroidism. It took me 12 weeks to get my thyroid normalized with the dose adjustments. However during this 12 weeks I did not have my periods. So the last period I had was on March 21st. Then my endocrinologist suggest a full blood work of all of my hormones. Last week when I met her she told me that I have PCOS because my Testosterone levels were high and progesterone low. Now she has put me on the current medications:
Synthoroid
Provera to get my periods started (only for 10 days)
Metformin
My question to you are the following:
1. When can i start Metformin?
2. Since the success rate is more with Metformin and Clomid combination, should I ask my endocrinologist to prescribe me with Clomid ?( as she has asked me be on Metformin for 3 months before she can prescribe me Clomid, because she wants to check whether my hormones are levelled with Metformin itself)
Please let me know
Naaz
I am 27 years old and my husband and I have been TTC since 7 months. I was on BCP till Nov'07. I did not get periods for the month of Dec. I got periods starting Jan to March which were really irregular. I could not determine when was I ovulating. My Ob/Gyn referred me to an endocrinologist because i have hypothyroidism. It took me 12 weeks to get my thyroid normalized with the dose adjustments. However during this 12 weeks I did not have my periods. So the last period I had was on March 21st. Then my endocrinologist suggest a full blood work of all of my hormones. Last week when I met her she told me that I have PCOS because my Testosterone levels were high and progesterone low. Now she has put me on the current medications:
Synthoroid
Provera to get my periods started (only for 10 days)
Metformin
My question to you are the following:
1. When can i start Metformin?
2. Since the success rate is more with Metformin and Clomid combination, should I ask my endocrinologist to prescribe me with Clomid ?( as she has asked me be on Metformin for 3 months before she can prescribe me Clomid, because she wants to check whether my hormones are levelled with Metformin itself)
Please let me know
Naaz
August 10, 2007
I think a reconsideration of your treatment is necessary. You should be having periods on your own with treatments, and if not and not trying to get pregnant, you should be on birth control pills for the estrogenic bone protective effects given your profile. Metfomin, although can be recommended for thin PCOS patients with proven insulin resistance, you may not be one of them. You may be one with a hypothalamic pulse generator "imbalance" creating a greater amount of LH/FSH giving your symptoms.
If you're trying to get pregnant, and RE can easily do so with very low doses of injectable gonadotropins. If you're not trying to get pregnant, maybe being on the pill is the best answer for you. These are common issues that we encountered that are normally addressed this way. Let us know if we can be of further assistance