There was much promise in the USA about the use of Avandia, as in theory it should work better than metformin given that it directly works to "fix" the insulin resistance that can create PCOS...much research was being done on Avandia...
Most all of this unfortunately came to a halt given that it received a "black box" label, meaining that it can be "dangerous" to take...The evidence for this was lacking given that the study that showed this was poor...Nevertheless, it received much negative press that it was felt "something should be done"...Attempts to remove it from the market failed though as many in the FDA felt that the study wasn't adequate enough to do so...
Mind you, these results may not fully apply to those ttc as the average person for whom this applies was 65 y/o and overtly diabetic...With proper counseling, could still be of benefit and may also promote weight loss....
Most all of this unfortunately came to a halt given that it received a "black box" label, meaining that it can be "dangerous" to take...The evidence for this was lacking given that the study that showed this was poor...Nevertheless, it received much negative press that it was felt "something should be done"...Attempts to remove it from the market failed though as many in the FDA felt that the study wasn't adequate enough to do so...
Mind you, these results may not fully apply to those ttc as the average person for whom this applies was 65 y/o and overtly diabetic...With proper counseling, could still be of benefit and may also promote weight loss....
June 15, 2008