January 30, 2009
I have had 2 m/c in the 1st trimester. I had multiple tests done but the only numbers that came back close to being out of range were the PAI-1 which read 43 (I was told normal was 4-43) and my Homocysteine, Nutritional and Congenital, which read 4.6 (I was told normal was 5.4-11.9). My online research makes me think the Homocysteine is only a problem if it is too high, so that leaves me with the PAI-1 of 43. Could this be the problem?
The tests were done at 10 weeks, the day we just saw only yolk sac in the ultrasound.
January 30, 2009
The most likely cause of miscarriages continues to be a chromosomally abnormal embryo.
The likelyhood of PAI-1 creating a miscarriage and/or homocysteine is very low. However, many REs irrespective of this information may elect to treat if one understands and is willing to take on the risks of treatment, those particularly of Heparin